Skip to main content
. 2000 Mar 15;105(6):765–775. doi: 10.1172/JCI8624

Figure 3.

Figure 3

Airway inflammatory responses and serum antibody production in i.n. OVA–sensitized IL-4–/–mice. C57BL/6 (WT) or IL-4–/– mice were initially exposed to i.n. OVA (100 μg) on days 0–2, and then challenged with i.n. OVA (25 μg) on days 14, 15, 18, and 19. (a) On day 21, mice were sacrificed, BAL was performed, and total cell yield and differential counts in cytospin preparations from individual mice were determined. Data were pooled from 2 experiments and are reported as mean ± SEM of 8 (WT) or 9 (IL-4–/–) mice per group. Both the total number of cells recovered by BAL and the number of each cell type are shown. Statistical significance between WT and IL-4–/– groups was determined by unpaired Student’s t test. (b) Serum was obtained for measurement of antibodies by ELISA on day 21. Data points represent values for individual mice with the mean indicated, and are from 1 representative experiment of 2 with similar results.