Table 3. Effects of various stimuli on NOP and PNoc mRNA expression in human whole blood.
Stimulation | NOP mRNA | PNoc mRNA |
LPS 10 ng/ml | ↓↓↓ | ↓↓ |
IL-10 50 ng/ml | ↓↓ | ↓ |
TNF-α 3 ng/ml | ↓↓ | → |
IL-1β 3 ng/ml | ↓↓ | → |
IFN-γ 10 ng/ml | ↓↓ | → |
Suppressive effect: ↓, ∼25%; ↓↓, ∼50%; ↓↓↓, ∼75%; →, no significant change compared to base line.