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. 2013 Sep 16;8(9):e74122. doi: 10.1371/journal.pone.0074122

Figure 6. Over-expression of mtfA increases penicillin production.

Figure 6

A) Extracts from wild-type (WT) veA+ control (TRV50.1), and over-expression (OE) mtfA strain (TRV60) were analyzed for penicillin content as described in Materials and Methods section. B) qRT-PCR expression analysis of acvA from mycelial samples collected after 24 h and 48 h of incubation in PN inducing medium. C) Northern blot analysis of ipnA and aatA from samples collected after 24 h and 48 h of incubation in PN inducing medium. Densitometries were carried out with the Scion Image Beta 4.03 software.