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Relatively reduced serum cholesterol levels in ACAT1–/–ApoE–/– mice compared with ACAT1+/+ApoE–/– mice. Serum cholesterol levels in mice fed a chow diet (a) or a Western diet (b). (c and d) Total cholesterol levels for pooled serum (n = 5 in each group) fractionated by FPLC. AP < 0.001, BP = 0.002.
