Figure 2.

Correlation analyses between baseline virological measures in blood and lymph and the time required to suppress HIV-1 RNA below 50 copies/mL. (a) Correlation between baseline plasma HIV-1 RNA levels and time to suppress HIV-1 RNA below 50 copies/mL. (b) Correlation between baseline number of virus-expressing cells in lymph node and time to suppress HIV-1 RNA below 50 copies/mL. (c) Correlation between baseline FDC-associated HIV-1 RNA in lymph node and time to suppress HIV-1 RNA below 50 copies/mL. Plasma HIV-1 RNA levels are expressed in log₁₀ copies per milliliter, the number of HIV-1–expressing cells is expressed in lymph node log₁₀ cells/100 mm² of lymphoid tissue, and FDC-associated HIV-1 RNA levels in lymph node are expressed in log₁₀ VGE per square millimeter of lymphoid tissue; 1 VGE corresponds to 2 HIV-1 RNA copies. The regression lines are shown. Quantitation of plasma viremia and of the number of virus-expressing cells in lymph node were performed as described in Methods. A 2-tailed P value < 0.05 was considered significant.