Table 1. Forest type, location, approximate area of each forest reserve, and mean annual temperature and rainfall of collection sites; number of host plant families collected (minimum number of genera, minimum number of genotypes); number of endophytic fungi isolated and isolates sequenced (number of genotypes); and number of isolates (minimum number of genotype groups) tested in each bioassay.
| Endophytes | Fungal Isolates Tested in Bioassays | ||||||||||||
| Collection Site | Forest Type | Approx. Location | Forest Area (km2) | Mean Annual Temp (°C) | Mean Annual Precip (mm) | Host Plant Samples | Host Plant Families | Isolated | Sequenced | Malaria | Leish-maniasis | Chagas' Disease | Cancer |
| Altos de Campana National Park | Cloud | 8°41”N /79° 55”W | 42.9 | 24 | 2500 | 175 | 41 (35, 13) | 204 | 21 (18) | 131(7) | 152 (9) | 147 (9) | 161 (11) |
| Barro Colorado Island | Lowland Humid | 9°94”N /79° 47”W | 112 | 28 | 2600 | 903 | 63 (115, 118) | 903 | 512 (152) | 644 (118) | 724 (131) | 733 (130) | 703 (130) |
| Chagres National Park | Lowland Dry, Humid; Cloud | 9°14”N /79° 22”W | 1311.4 | 30 | 3100 | 480 | 21 (19, 13) | 480 | 67 (44) | 377 (35) | 380 (35) | 393 (36) | 390 (36) |
| Coiba National Park and Buffer Zones | Lowland Humid | 7°30”N /81° 51”W | 523.7 | 26 | 3500 | 952 | 39 (66, 54) | 1032 | 459 (143) | 407 (72) | 625 (123) | 622 (114) | 649 (122) |
| Fortuna Forest Reserve | Cloud | 8°40”N /81° 21”W | 206.5 | 20 | 5500 | 171 | 4 (4, 2) | 171 | 0 | 159 (na) | 150 (na) | 163 (na) | 157 (na) |
| G.D. Omar Torrijos Herrera National Park | Cloud | 8°40”N /81° 35”W | 262.2 | 25 | 3000 | 142 | 20 (na) | 142 | 1 (1) | 121 (na) | 128 (1) | 130 (1) | 132 (1) |
| Montuosa Island Wildlife Refuge | Lowland Humid | 7°28”N /82° 14”W | 0.8 | 26 | 3500 | 206 | 14 (na) | 206 | 0 | 200 (na) | 199 (na) | 202 (na) | 200 (na) |
| Sarigua National Park | Lowland Dry | 7°40”N /80° 35”W | 46.6 | 27 | 1100 | 51 | 3 (na) | 51 | 21 (11) | 13 (5) | 14 (11) | 14 (5) | 15 (5) |
| Soberania National Park | Lowland Humid | 9°71”N /79° 42”W | 195.4 | 28 | 2200 | 118 | 12 (na) | 118 | 63 (35) | 69 (21) | 85 (28) | 70 (21) | 87 |
| Total Isolates (minimum number genotypes) | 3307 | 1144 (291) | 2121 (196) | 2457 (245) | 2474 (237) | 2495 (244) | |||||||
| Total Highly Active Isolates (%) | 358 (16.9) | 378 (15.4) | 99 (4.1) | 140 (5.6) | |||||||||
Because a high proportion of plants and fungi represent previously unknown or undescribed species, and not all collections or isolates were determined taxonomically, “minimum number” values refer to the subsets of plant and fungal samples that were identified to fine taxonomic levels.