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. 2013 Sep 16;8(9):e73192. doi: 10.1371/journal.pone.0073192

Table 4. Activity of crude extracts from fungal endophytes against Leishmania donovani (causative agent of leishmaniasis) in in vitro assays, organized by fungal family.

Family (Order) Mean %IG (± SE) Fungal Genotypes Examined Highly Active Genotypes % Highly Active Genotypes Activity Level
Nectriaceae (Hypocreales) 34.9 (7.9) 7 2 28.6 High
Trichocomaceae (Eurotiales) 21.9 (5.2) 16 2 12.5 High
Mycosphaerellaceae (Capnodiales) 20.4 (5.2) 15 3 20 High
Amphisphaeriaceae (Xylariales) 18.8 (7.9) 7 0 0 Moderate
Xylariaceae (Xylariales) 17.7 (3.1) 46 6 13.1 Moderate
Valsaceae (Diaporthales) 15.8 (3.8) 31 1 3.2 Moderate
Botryosphaeriaceae (Botryosphaeriales) 15.5 (7.9) 7 0 0 Moderate
Phyllachoraceae (Phyllachorales) 9.5 (5.1) 17 0 0 Low
Boliniaceae (Boliniales) 7.9 (9.4) 5 0 0 Low
Magnaporthaceae (Magnaporthales) 3.9 (9.4) 5 0 0 Low

Data indicate mean percent inhibition of growth of parasite cells (mean % IG) and standard error, the number of fungal genotypes examined, the number and percent of those genotypes that are highly active (i.e., ≥50% IG), and a qualitative statement of activity level. Mean % IG varied significantly among activity levels (F2, 153 = 4.45; p = 0.0132).