Table 2. Information on studies included.

study	reference	population	sample collection	# TB patients	type of sample
				initial, independent
1	Mistry R, JID, 2007: 195, 357	active TB disease vs healthy infected controls	South Africa	n = 10	whole blood
2	Jacobsen M, J Mol Med, 2007: 85, 613	active TB disease vs healthy infected controls	Germany	n = 9	PBMC
3	Berry MP, Nature, 2010: 466, 973	active TB disease vs healthy infected & uninfected controls vs other inflammatory disorders (SLE, Stills, Streptococcus, Staphylococcus)	United Kingdom (test), South Africa (validation)	n = 13, n = 20	whole blood
4	Maertzdorf J, Genes & Immunity, 2011: 12, 15	active TB disease vs healthy infected & uninfected controls	South Africa	n = 33	whole blood
5	Maertzdorf J, PLoS ONE, 2011: 6, e26938	active TB disease vs healthy infected & uninfected controls	The Gambia	n = 46	whole blood
6	Maertzdorf J, PNAS, 2012: 109, 7853	active TB disease vs heatlhy infected & uninfected controls & sarcoidosis	Germany	n = 8	whole blood
7	Cliff J, JID, 2013: 207, 18	active TB disease over time during treatment	South Africa	n = 27, n = 9	whole blood
8	Ottenhoff TH, PLOS ONE, 2012: 7, e45839	active TB disease over time during treatment vs healthy controls	Indonesia	n = 23	PBMC