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Figure 1. Schematic images of adipogenesis involving histone methyltranferases and demethylases that interact with adipogenesis-related transcription factors. MLL3 and MLL4 facilitate adipogenesis mediated by the PPARG/ASC-2 complex. CEBPA-mediated adipogenesis can be regulated positively by PHF2 as well as LSD1 and negatively by SETDB1.
