Table 1. Global parameters of CA/CPR.
| WT | TLR2-/- | WT + T2.5 | |
|---|---|---|---|
| n = 31 | n = 30 | n = 15 | |
| baselinebeforepreparationforCA/CPR | |||
| body weight [g] | 22,3 ± 1,4 | 22,1 ± 0,6 | 21,2 ± 0,8 |
| heart rate [1/min] | 218 ± 24 | 229 ± 40 | 224 ± 21 |
| mean arterial pressure [mm Hg] | 95 ± 13 | 102 ± 13 | 97 ± 17 |
| body temperature [°C] | 36,1 ± 0,3 | 36,2 ± 0,1 | 36,3 ± 0,1 |
| parameterofCA/CPR | |||
| time ROSC [sec] | 80 ± 15 | 73 ± 20 | 66 ± 26 |
| successfully resuscitated animals [%] | 100 | 100 | 100 |
| dosage of epinephrine [µg] | 10 [10-20] | 10 [10-15] | 10 [10-15] |
| weaning from mech. ventilation [min] | 150 ± 20 | 128 ± 17* | 113 ± 20* |
| 1hourafterCA/CPR | |||
| heart rate [1/min] | 401 ± 101 | 358 ± 75 | 365 ± 80 |
| mean arterial pressure [mm Hg] | 83 ± 21 | 75 ± 17 | 80 ± 25 |
| body temperature [°C] | 36,1 ± 0,1 | 36,0 ± 0,3 | 36,1 ± 0,2 |
Analysis of global parameters of CA/CPR. There were no significant differences between the groups, except the time needed for weaning from mechanical ventilation.
Data are presented as median and [25-75] percentiles and were analysed employing ANOVA/Bonferroni. *P < 0.05 WT vs. TLR2-/-; #P < 0.05 WT vs. WT+T2.5