Table 3. Results and Analysis of spatial learning employing Water Maze Test.

WaterMazeTest	WT	WT + T2.5	TLR2-/-
	n = 31	n = 15	n = 30
TrainingphasebeforeCA/CPR (time [sec])
first attempt (day -5)	13 [8-38]		14 [9-19]
last attempt (day -1)	9 [3-23]*		16 [9-39]
ParticipationintheWaterMazeTestafterCA/CPR
participants after CA/CPR
n [%]	16/31 [52]	12/15 [80]#	23/30 [77]&
earliest day of
participation after CA/CPR	5 [3-11]	3 [3-4]#	3 [3-6]&
(day X)
TestafterCA/CPR (time [sec])
first attempt (day X)	9 [4-21]	8 [7-30]	16 [7-23]
last attempt (day X + 5)	6 [3-11]	2 [2-7]§	16 [6-31]

Results from neurological evaluation employing the Water Maze Test. Mice were trained daily (twice a day, five attempts in each session) beginning 5 days prior to CA/CPR; results from the first and last attempt of the training phase are shown in the upper third of the table. *P < 0.05 WT day - 5 vs. day - 1 Participation of mice after CA/CPR (defined as day X) was restricted to animals that met the requirements for participation (i.e. 12 points in the NeuroScore, a completed attempt in the RotaRod Test (300 s), halt in loss of body weight and no signs of disturbance). Number and earliest time point of participation of mice in the Water Maze Test following CA/CPR is presented in the middle part of the table. #P < 0.05 WT vs. WT+T2.5; & P < 0.05 WT vs. TLR2^-/-. First and last attempt of mice after CA/CPR is presented in the lower third of the table. §P < 0.05 WT+T2.5 day X vs. WT+T2.5 day X+5. Data is presented as median and [25-75] percentiles and was analysed employing ANOVA/Bonferroni and Chi-Square test for participants after CA/CPR.