Table 4. Results of inflammatory response after cardiac arrest and resuscitation.
WT
|
TLR2-/-
|
WT + T2.5 antibody
|
||||
---|---|---|---|---|---|---|
n = 6 |
n = 6 |
n = 6 |
||||
baseline | 8 h after CA/CPR | baseline | 8 h after CA/CPR | baseline | 8 h after CA/CPR | |
Corticosteron [nmol/L] | 96 ± 3 | 932 ± 125 | 98 ± 3 | 1269 ± 66 *# | 95 ± 3 | 801 ± 95 |
Interleukin-1β [pg/mL] | 0.5 ± 0.1 | 0.7 ± 0.3 | 0.2 ± 0.1 | 0.4 ± 0.3 | 0.4 ± 0.1 | 0.9 ± 0.2 |
Interleukin-6 [pg/mL] | 18 ± 11 | 1949 ± 449 | 46 ± 13 | 237 ± 48 *# | 22 ± 9 | 2167 ± 307 |
Plasma levels of corticosterone and interleukin-1β and interleukin-6 (IL-1β and IL-6) at baseline and eight hours following CA/CPR. Data is presented as mean ± SD and was analysed by ANOVA/Bonferroni. Eight hours after CA/CPR: *P < 0.05 WT vs. TLR2-/-; #P < 0.05 WT vs. WT+T2.5