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. 2013 Sep 16;8(9):e74605. doi: 10.1371/journal.pone.0074605

Table 2. iORFV (D1701) reduces antigen cross-presentation by liver sinus endothelial cells (LSEC) but enhances activation of T-cells.

antigen LSEC+B3Z+PBS (mock-treated) LSEC+B3Z+ iORFV comparison vs. mock-treated LSEC (100%)
ovalbumin 1084 pg/ml IL2 236 pg/ml IL2 22%
SIINFEKL 1780 pg/ml IL2 3043 pg/ml IL2 168%

Activation of CD8+ T cells (B3Z) was measured by IL-2 secretion.