Figure 1. Effect of chronic hypoxia on HIF-1α protein expression in uterine arteries.

Uterine arteries were isolated from near-term pregnant and nonpregnant sheep maintained at sea level (control) or exposed to high-altitude hypoxia for 110 days. Protein abundance of HIF-1α was determined by Western blot analyses. Data are means ± SEM of tissues from 4 animals of each group, *, P<0.05, versus control.