Figure 4. Effect of chronic hypoxia on Nox activity in uterine arteries.

Uterine arteries were isolated from near-term pregnant and nonpregnant sheep maintained at sea level (control) or exposed to high-altitude hypoxia for 110 days. NADPH oxidase activity (Nox) was measured by lucigenin luminescence in the uterine arteries. Data are means ± SEM of tissues from 5 animals of each group, *, P<0.05, versus control.