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. 2013 Sep 16;8(9):e73913. doi: 10.1371/journal.pone.0073913

Figure 2. Quantitative changes in total CFs for RF-induced rat sciatic nerve injury.

Figure 2

CF, collagen fiber. RF, radiofrequency. (A) CO and SH groups showed normal collagen structure encasing NFs while the RF groups showed significant decreases in total collagen density. CO, control; SH, sham; PRF, pulsed RF; CRF, continuous RF. CF = epi-perineurial layer; NF, nerve fiber = endoneurial layer. Scale bar = 250 µm. (B) Ratios of total collagen for each treatment group normalized against the CO group. COL, collagen. Data shown are the mean and SD of six mice (n = 18). *P<0.05; ***P<0.0001 vs. CO.