Table 2. Associations between 2-year program attrition and individual-level factors among all patients and in the subgroup of patients with less severe HIV disease.
| Individual factors |
All patients
|
Less severe patients
|
||||
|---|---|---|---|---|---|---|
| Crude IRR(95% CI) |
Adjusted IRR (95% CI) |
Crude IRR (95% CI) |
Adjusted IRR (95% CI) |
|||
| Type of provider | p<0.001 | p<0.001 |
P<0.001 | p<0.001 |
||
| Nurse | 1 | 1 |
1 | 1 |
||
| Mixed | 0.60 (0.50-0.73) | 0.54 (0.45-0.65) |
0.52 (0.38-0.71) | 0.59 (0.43-0.81) |
||
| Clinical officer | 4.71 (4.02-5.51) | 3.03 (2.56-3.59) |
3.69 (2.82-4.82) | 3.47 (2.63-4.58) |
||
| Sex | p<0.001 | p<0.001 | p<0.001 | p<0.001 | ||
| Male | 1 | 1 | 1 | 1 | ||
| Female | 0.52 (0.47-0.57) | 0.75 (0.68-0.82) | 0.55 (0.44-0.69) | 0.64 (0.51-0.81) | ||
| Initial BMI, kg/m2 | p<0.001 | p<0.001 | p=0.62 | p=0.43 | ||
| <18.5 | 1 | 1 | ||||
| 18.5-24.99 | 0.42 (0.38-0.46) | 0.56 (0.50-0.62) | 1 | 1 | ||
| ≥25 | 0.34 (0.27-0.44) | 0.40 (0.31-0.51) | 0.91 (0.63-1.33) | 0.86 (0.59-1.26) | ||
| Unknown | 3.30 (2.36-4.61) | 1.42 (1.00-1.99) | ||||
| Initial clinical stage | p<0.001 | p<0.001 | p=0.005 | p=0.03 | ||
| 1 | 1 | 1 | 1 | 1 | ||
| 2 | 1.43 (1.22-1.68) | 1.27 (1.08-1.50) | 1.38 (1.11-1.72) | 1.27 (1.02-1.59) | ||
| 3 | 2.30 (1.99-2.66) | 1.23 (1.06-1.43) | ||||
| 4 | 4.17 (3.60-4.82) | 1.48 (1.26-1.74) | ||||
| Unknown | 1.91 (1.57-2.33) | 1.40 (1.15-1.72) | ||||
| Initial CD4 count, cells/µL | p<0.001 | p<0.001 | p=0.20 | p=0.31 | ||
| <50 | 1 | 1 | ||||
| 50-99 | 0.60 (0.51-0.72) | 0.78 (0.66-0.93) | ||||
| 100-199 | 0.42 (0.36-0.48) | 0.83 (0.71-0.97) | 1 | 1 | ||
| 200-249 | 0.31 (0.26-0.37) | 0.71 (0.59-0.85) | 0.80 (0.63-1.02) | 0.83 (0.65-1.06) | ||
| ≥250 | 0.53 (0.45-0.63) | 0.90 (0.75-1.07) | 0.88 (0.64-1.19) | 0.96 (0.70-1.32) | ||
| Unknown | 0.95 (0.79-1.15) | 1.07 (0.88-1.29) | ||||
| Year of ART initiation | p=0.02 | p=0.02 | p=0.03 | p=0.10 | ||
| 2007 | 1 | 1 | 1 | 1 | ||
| 2008 | 1.06 (0.91-1.24) | 1.02 (0.87-1.19) | 1.21 (0.81-1.81) | 1.00 (0.67-1.50) | ||
| 2009 | 1.10 (0.94-1.28) | 0.90 (0.77-1.06) | 1.60 (1.08-2.37) | 1.30 (0.87-1.94) | ||
| 2010 | 1.40 (1.13-1.74) | 0.78 (0.63-0.97) | 1.56 (0.90-2.68) | 0.90 (0.52-1.57) | ||
| Adherence index | p<0.001 | p<0.001 | p<0.001 | p<0.001 | ||
| ≥95% | 1 | 1 | 1 | 1 | ||
| 80-94% | 0.42 (0.37-0.47) | 0.39 (0.35-0.45) | 0.50 (0.38-0.66) | 0.49 (0.38-0.65) | ||
| <80% | 3.62 (3.22-4.06) | 1.84 (1.63-2.07) | 4.46 (3.39-5.87) | 2.84 (2.14-3.76) | ||
| Period of follow-up, months | p<0.001 | p<0.001) | p<0.001 | p<0.001 | ||
| ≤3 | 1 | 1 | 1 | 1 | ||
| 4-6 | 0.41 (0.36-0.47) | 0.48 (0.42-0.55) | 0.42 (0.30-0.59) | 0.46 (0.33-0.64) | ||
| 7-24 | 0.21 (0.19-0.24) | 0.28 (0.25-0.31) | 0.29 (0.23-0.37) | 0.33 (0.26-0.43) | ||
Note: ART, antiretroviral therapy; BMI, body mass index; CI, confidence interval; IRR, incidence rate ratio.