Table 1.
Namea | Sequence (5' to 3')b | Locationc |
---|---|---|
3'-end RNA ligation linker | rAppTTTAACCGCGAATTCCAG/ddC | |
5'-end RNA ligation linker | TGGAATrUrCrUrCrGrGrGrCrArCrCrArArGrGrU | |
miRNA-RT | GCTGGAATTCGCGGTTAA | |
miRNA-Forward | TGGAATTCTCGGGCACCA | |
F | CGGCTTGAGGCCAAGAAC | 61E U3LTR −197 to −180 |
R | TCGAACTCTGGTCAACTG | 61E U3LTR −94 to −111 |
M6 | ACTGGGGAGCtcGGAGACTGC | 61E U3LTR −108 to −128 |
M7 | ATAGCAGAAttCGCGCGTACA | 61E U3LTR −28 to −48 |
FeLV EnvA | GTCAGGACAATAACTGTGAGG | 61E gp70 6167 to 6187 |
FeLV EnvB | CGGTCCCAATCCGTTTGGGAC | 61E gp70 6499 to 6479 |
T7-F | TAATACGACTCACTATAGGCGGCTTGA--GGCCAAGAAC | T7 promoter at the 5' of `F' |
Ligation linkers were purchased from Integrated DNA Technologies.
bases with a prefix `r' denote ribonucleotides, dd is dideoxynucleotide, lower case letters in M6 and M7 denote deviation from original sequence introduced to create restriction enzyme sites. T-7 promoter binding site is underlined in oligonucleotide primer T7-F.
Locations of the oligonucleotide primers are based on FeLV-A 61E sequence (Genbank accession number M18247) where +1 is the beginning of the genomic RNA transcript at R.