Table 3.
The results of ROC analysis for discriminating impaired from non-impaired FMD.
| AUC (95% CI) | Std. error | Sensitivity % | Specificity % | AUC (95% CI)b | P | |
|---|---|---|---|---|---|---|
| SDMA | 0.689 (0.549–0.829) | 0.071 | 81.8 | 58.3 | 0.686 (0.540–0.820) | 0.007 |
| hs-CRP | 0.754 (0.602–0.905) | 0.054 | 73.3 | 75.8 | 0.735 (0.628–0.840) | <0.001 |
| IL-6 | 0.699 (0.597–0.802) | 0.052 | 72.3 | 52.6 | 0.690 (0.579–0.789) | 0.002 |
| SAA | 0.605 (0.486–0.725) | 0.061 | 76.7 | 51.4 | 0.093 | |
| O2∙− | 0.593 (0.467–0.719) | 0.064 | 69.2 | 34.5 | 0.174 | |
| Model: hs-CRP and SDMA | 0.730 (0.582–0.878) | 0.076 | 0.728 (0.592–0.855) | 0.005 | ||
| Model: hs-CRP and O2∙− | 0.671 (0.531–0.812) | 0.072 | 0.639 (0.517–0.771) | 0.025 | ||
| Model: hs-CRP, SDMA, and O2∙− | 0.756 (0.623–0.888) | 0.068 | 0.741 (0.616–0.859) | 0.004 | ||
| Model: IL-6 and SDMA | 0.732 (0.614–0.851) | 0.061 | 0.704 (0.593–0.813) | 0.001 | ||
| Model: IL-6 and O2∙− | 0.628 (0.507–0.749) | 0.062 | 0.070 | |||
| Model: IL-6, SDMA, and O2∙− | 0.724 (0.570–0.878) | 0.079 | 0.715 (0.566–0.846) | 0.003 | ||
| Model: SDMA and O2∙− | 0.737 (0.598–0.876) | 0.071 | 0.655 (0.533–0.778) | 0.002 |
Data in parentheses are 95% confidence intervals (95% CIs). Sensitivity and specificity were calculated for optimal cutoff value. bThe AUC and 95% confidence intervals of the 1000 bootstrap samples.