Figure 5.
EUK139 or tempol added after irradiation improves survival of irradiated zebrafish. Fish were irradiated to 30 Gy, placed in water containing amifostine (20 μM), tempol (1 mM), EUK139 (50 μM) or vehicle control and followed for survival. Zebrafish treated with EUK139, Amifostine or Tempol after irradiation showed an increased survival compared to control fish. Drugs added pre-irradiation were toxic.