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. 2013 Oct;45(10):2121–2129. doi: 10.1016/j.biocel.2013.04.023

Fig. 1.

Fig. 1

Signaling modules responsible for autophagy-lysosome pathway in the adult. The different modules are: autophagosome formation, selective autophagic removal of mitochondria, autophagosome docking and fusion with lysosome and new lysosome formation. Each module is controlled by different pathways and factors. The dotted lines point to mechanisms that are not yet known.