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. 2013 Sep 17;4:106. doi: 10.3389/fpsyt.2013.00106

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Copyright © 2013 McNally, McCarley and Brown.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chronic MK-801 treatment does not significantly alter KA-elicited PrL oscillations. Graphs show the effects of chronic MK-801 given at daily doses of 0.02 mg/kg (blue) or 2 mg/kg (red) on (A) total GBO power (40–50 Hz), (B) peak power, and (C) peak frequency across 30 s of the elicited oscillatory response recorded from acute PrL slices, compared to saline treated controls (black). At both concentrations chronic MK-801 treatment resulted in no significant alteration of KA-elicited oscillatory activity.