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. Author manuscript; available in PMC: 2013 Sep 17.
Published in final edited form as: Curr Neurobiol. 2010 Mar;1(1):70–76.

Figure 3. Developmental PCB exposure increases cerebellar apoptosis as detected by TUNEL.

Figure 3

Representative photomicrographs of TUNEL staining in sections of cerebellum from PND3 rats exposed developmentally to vehicle (A) or A1254 at 1 mg/kg/d in the maternal diet (B). Quantification of the number of cells labeled by TUNEL, which detects DNA fragmentation, confirms significantly increased apoptosis in the cerebellum of A1254-exposed rats relative to vehicle controls (C). Data presented as the mean ± SEM (N = 16 fields per treatment group); ***p<0.001 (unpaired t-test).