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. 2013 Sep 17;4:282. doi: 10.3389/fimmu.2013.00282

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Copyright © 2013 Van Braeckel-Budimir, Haijema and Leenhouts.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Influenza-specific IgA titers measured in nasal lavages of vaccinated subjects. Nasal lavages of study subjects were collected and IgA titers assessed on study days 0 (baseline), 21, and 42. On both days 21 and 42 titers measured in nasal lavages of subjects vaccinated i.n. with FluGEM-A were significantly higher than titers measured in lavages of subjects vaccinated i.n. with TIV. Increase in nasal IgA titers in FluGEM-A vaccination group relative to the baseline was approximately 100% by day 21. *p < 0.05; one-tailed Mann–Whitney U test.