Table 5.
(Top) Mitochondrial dysfunction-related genes with expression correlated with SST (14/174 genes) in human frontal cortex. (Bottom) GABA receptor signaling-related genes with expression correlated with SST (8/56 genes).
| Gene symbol | Gene title | Gene accession | Correlation with SST (R) |
|---|---|---|---|
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | NM_001686 | 0.759 |
| COX8A | Cytochrome c oxidase subunit VIIIA (ubiquitous) | NM_004074 | 0.771 |
| CYC1 | Cytochrome c-1 | NM_001916 | 0.748 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39 kDa | NM_005002 | 0.742 |
| NDUFA11 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7 kDa | NM_175614 | 0.755 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8 kDa | NM_005003 | 0.788 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16 kDa | NM_002492 | 0.736 |
| NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase) | NM_004551 | 0.735 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13 kDa (NADH-coenzyme Q reductase) | NM_004553 | 0.767 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa | NM_007103 | 0.754 |
| PINK1 | PTEN induced putative kinase 1 | NM_032409 | 0.74 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex | NM_006830 | 0.735 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske | NM_006003 | 0.812 |
| UQCRH | ubiquinol-cytochrome c reductase hinge | NM_006004 | 0.777 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | NM_004069 | 0.78 |
| GABBR2 | Gamma-aminobutyric acid (GABA) B receptor, 2 | NM_005458 | 0.75 |
| GABRA3 | Gamma-aminobutyric acid (GABA) A receptor, alpha 3 | NM_000808 | 0.73 |
| GABRA5 | Gamma-aminobutyric acid (GABA) A receptor, alpha 5 | NM_000810 | 0.746 |
| GABRB3 | Gamma-aminobutyric acid (GABA) A receptor, beta 3 | NM_021912 | 0.748 |
| GAD67 | Glutamate decarboxylase 67 (brain, 67 kDa) | NM_000817 | 0.736 |
| GAD65 | Glutamate decarboxylase 65 (pancreatic islets and brain, 65 kDa) | NM_000818 | 0.791 |
| SLC32A1 | Solute carrier family 32 (GABA vesicular transporter), member 1 | NM_080552 | 0.773 |