Figure 2.

Schematic depiction of chromosome 10 showing the probe locations of the PTEN four-color FISH assay; based on Yoshimoto et al. (29). The four-color FISH assay was designed to include BMPR1A (green) and FAS (aqua) probes flanking either side of the 2.06-Mb minimal deleted region, a PTEN probe (orange) at 10q23.3 and a chromosome 10 centromere (red) copy control probe.