Table 1.

Mutations in the PTEN gene identified in prostate cancer.

Exon	Position	Predicted effect	Reference
Exon 1	G20STOP	Non-sense	Dong et al. (55)
Exon 2	R55G	Missense	Dong et al. (55)
Exon 3	T38G	Inactivation	Krohn et al. (40)
Exon 5	E91Q	Inactivation	Suzuki et al. (7)
	R387STOP	Non-sense	Suzuki et al. (7)
	H118Y	Inactivation	Krohn et al. (40)
	I101A	Missense	Dong et al. (55)
	I135V	Missense	Dong et al. (55)
	Q150G	Missense	Dong et al. (55)
	Q110STOP	Non-sense	Dong et al. (55)
	P95S	Missense	de Muga et al. (63)
	A164STOP	Non-sense	de Muga et al. (63)
Exon 6	564	Non-sense	Cairns et al. (49)
Exon 7	c.761–765del	Frameshift	Cairns et al. (49)
	c.672–673Ins	Non-sense	Suzuki et al. (7)
	c.224Ins	Frameshift	Suzuki et al. (7)
	D223N	Missense	de Muga et al. (63)
Exon 8	E201STOP	Non-sense	Krohn et al. (40)
	D326N	Inactivation	Krohn et al. (40)
	H272Y	Missense	Dong et al. (55)
Exon 9	T348I	Missense	Dong et al. (55)
	K344R	Missense	Dong et al. (55)
	T382S	Missense	Dong et al. (55)