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Methodologies used to overproduce drugs using engineered transcriptomics approach.
| Strains | Drugs | Approach | Methodologies |
|---|---|---|---|
| Streptomycetes | Antibiotics | Engineered Transcriptomics | TetR family transcriptional regulator as a global upregulator for enhanced antibiotic production |
| S. peucetius OIM | Doxorubicin and Daunorubicin | Engineered Transcriptomics | Disruption of wblA from S. peucetius OIM resulted in increase in the production of both doxorubicin and daunorubicin |
