Table 2.
Effect of Vitamin D Supplementation on Blood Pressure during the Treatment Period (Baseline to 3 months)
| Parameter | Vitamin D dose (IU/day) | Entire study population (all doses) |
||||
|---|---|---|---|---|---|---|
| Placebo | 1000 | 2000 | 4000 | |||
| N (at baseline) | 72 | 68 | 73 | 70 | 283 | |
| N (at 3 months) | 64 | 56 | 65 | 65 | 250 | |
| N (difference) | 64 | 56 | 65 | 65 | 250 | |
| Within-group changes in BP |
3 month change in BP per 1000 IU/day |
p-value | ||||
| Baseline SBP, mean (SE) | 122.2 (2.2) | 124.7 (2.1) | 122.8 (2.0) | 130.4 (2.4) | − 1.4 (0.7) | 0.04 |
| 3 month SBP, mean (SE) | 124.9 (2.4) | 122.5 (2.0) | 120.0 (2.4) | 126.6 (2.6) | ||
| Difference SBP, mean (SE) | 1.7 (2.1) | −0.66 (2.1) | −3.4 (2.0) | −4.0 (2.1) | ||
| Baseline DBP, mean (SE) | 78.0 (1.3) | 79.8 (1.3) | 77.6 (1.4) | 79.8 (1.6) | − 0.5 (0.5) | 0.37 |
| 3 month DBP, mean (SE) | 78.9 (1.8) | 78.0 (1.6) | 76.0 (1.8) | 78.0 (1.6) | ||
| Difference DBP, mean (SE) | 0.7 (1.6) | −2.5 (1.6) | −1.8 (1.4) | −1.8 (1.50) | ||