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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Pediatr Res. 2013 Jan 23;73(4 0 1):484–491. doi: 10.1038/pr.2013.18

Table 4.

SNP haplotypes in the TSHR gene that are significantly associated (p<0.001) with natural log transformed TSH levels

SNPs
Gene Haplotype Frequency Beta P-value
TSHR rs10149689-rs4903957-rs11159483
AGT 0.06 −0.16 7.9×10−4
TSHR rs4903957-rs11159483-rs2075179
GTT 0.05 −0.16 6.2×10−4
TSHR rs10149689-rs4903957-rs11159483-rs2075179
AGTT 0.03 −0.28 4.2×10−5
TSHR rs4903957-rs11159483-rs2075179-rs12885526
GTTA 0.05 −0.17 7.8×10−4

Frequency: frequency of haplotype indicated. Beta: beta coefficient for linear regression model; positive value indicates the haplotype is associated with an increase in TSH level, negative value indicates the haplotype is associated with a decrease in TSH level. P-value = p-value for association between natural log transformed TSH and a specific haplotype composed of the alleles listed.