Table I.
Summary of the demographic and clinical characteristics of children in the Silent Infarct Transfusion Trial with and without magnetic resonance angiography-defined vasculopathy.
| Subject characteristics | Number of Participants | Vasculopathy (n = 53) | No vasculopathy (n = 463) | p-value |
|---|---|---|---|---|
| Silent infarcts (%) | 516 | 64.2 | 38.9 | 0.0004 |
| Male (%) | 516 | 58.5 | 50.5 | 0.27 |
| Mean age (years) | 516 | 9.0 | 9.2 | 0.62 |
| Mean Hb† | 516 | 82 | 82 | 0.91 |
| SBP# | 511 | 111.1 | 107.8 | 0.05 |
| WBC‡ | 514 | 14.54 | 12.351 | 0.42§ |
| Baseline oxygen saturation (%) | 498 | 96.1 | 96.9 | 0.06 |
| Acute chest syndrome rate* | 513 | 0.16 | 0.15 | 0.72 |
| Pain event rate** | 512 | 0.72 | 0.67 | 0.72 |
†
Steady state haemoglobin (g/l)
#
Steady state systolic blood pressure (mm Hg).
‡
Mean steady state white blood cell count (× 109/l)
§
p-value based on Student's t-test of log differences.
*
Acute chest syndrome event requiring hospitalization (per-person year).
**
Pain event requiring hospitalization (per person-year).