Table II.

Multivariate logistic regression models to predict vasculopathy among children the Silent Infarct Transfusion Trial.

Model 1: All Covariates
Variable	Odds Ratio	95% Confidence Interval	p-value
Silent Cerebral Infarct	2.77	1.49-5.18	0.001
Male	0.82	0.42-1.50	0.51
Age	0.91	0.80-1.04	0.15
Steady state Hb†	1.14	0.86-1.52	0.35
SBP#	1.02	1.00-1.05	0.09
WBC (log)‡	1.16	0.57-2.36	0.69
Baseline oxygen saturation	0.93	0.83-1.03	0.15
Acute chest syndrome rate*	0.89	0.32-2.45	0.82
Pain event rate**	1.03	0.74-1.43	0.87
Model 2: Only covariates with p<0.20 were retained from Model 1
Silent Cerebral Infarct	2.70	1.46-5.00	0.002
Age	0.92	0.81-1.04	0.19
Systolic blood pressure	1.02	1.00-1.05	0.08
Baseline oxygen saturation	0.93	0.84-1.03	0.18
Model 3: Only covariates with p<0.05 were included from Model 2
Silent Cerebral Infarct	2.84	1.55-5.21	0.0007

^†Steady state haemoglobin (g/l)

^#Steady state systolic blood pressure (mm Hg).

^‡Mean steady state white blood cell count (× 10⁹/l)

^*Acute chest syndrome event requiring hospitalization (per-person year).

^**Pain event requiring hospitalization (per person-year).