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. 2013 Sep 17;8(9):e74862. doi: 10.1371/journal.pone.0074862

Figure 3. Effect of trifluoperazine on the transport properties of Rhodamine 123 in L. donovani isolates.

Figure 3

A. Accumulation of Rho 123 after 1h loading (hatched bar1); accumulation in presence of TFP (mat bar). B. Retention of Rho 123 after 1 h of efflux (hatched bar), retention in presence of TFP at the time of accumulation (mat bar), retention in the presence of TFP at the time of efflux (white dotted bar). Results are mean of three independent experiments performed from three different promastigote cultures. * P ≤ 0.05, ** P ≤ 0.005, *** P ≤ 0.0005 indicate statistical significance with respect to sensitive isolate S1 for resistant isolates R5 and reference sensitive strain Dd8 for lab resistant Mt, ns indicates no statistically significant difference.