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. 2013 Sep 17;8(9):e75779. doi: 10.1371/journal.pone.0075779

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© 2013 McLeod et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Outbred Wistar rats underwent 1 h (n = 8), 2 h (n = 7) or permanent MCAo (n = 13) of the right middle cerebral artery (MCAo) using a silicone-tipped intraluminal filament. A. Infarct volume was quantified with histology at 24 h. Presence of anterior choroidal artery occlusion (AChAo) was determined by cerebral blood volume (CBV) map analysis. B. Cortical and sub-cortical infarct volume distribution in pMCAo animals (mean + sd). C. The traced infarct (seen in grey) from animals in the pMCAo group were overlaid so that lighter regions represent areas more commonly infarcted.