Table 5. Up-regulated genes: CVID w complications vs. CVID w/o complications.
| Gene | Name | FC* | Module |
|---|---|---|---|
| ANKRD22 | Ankyrin repeat domain 2 | 3.83 | |
| BATF2 | Basic leucine zipper transcription factor, | 3.85 | IFN |
| CMPK2 | Cytidine monophosphate (UMP-CMP) kinase 2 | 2.35 | IFN |
| CXCL10 | Chemokine (C-X-C motif) ligand 10 | 3.28 | IFN |
| EPSTI1 | Epithelial stromal interaction 1 | 3.50 | IFN |
| ETV7 | Ets variant 7 | 2.41 | IFN |
| FBXO6 | F-box protein 6 | 2.29 | IFN |
| FCGR1A | Fc fragment of IgG, high affinity Iα, receptor | 2.47 | |
| FCGR1B | Fc fragment of IgG, high affinity Iβ | 2.75 | |
| GBP1 | Guanylate binding protein 1 | 2.69 | IFN |
| GBP5 | Guanylate binding protein 5 | 2.93 | IFN |
| GBP6 | Guanylate binding protein 6 | 2.82 | IFN |
| IFI27 | Interferon, alpha-inducible protein 27 | 6.69 | IFN |
| IFI35 | Interferon-induced protein 35 | 2.30 | IFN |
| IFI44 | Interferon-induced protein 44 | 2.64 | IFN |
| IFI44L | Interferon-induced protein 44-like | 3.69 | IFN |
| IFI6 | Interferon, alpha-inducible protein 6 | 2.40 | IFN |
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 | 2.32 | IFN |
| IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 3.47 | IFN |
| IGFL2 | IGF-like family member 2 | 2.28 |
*
fold change.