Table 6. Down regulated genes: Healthy controls vs. All CVID.
| Gene | Name | FC* | Module |
|---|---|---|---|
| IGJ | Immunoglobulin J polypeptide | -12.86 | plasma cell |
| LRRN3 | Leucine-rich repeat neuronal protein 3 | -6.93 | T cell |
| IGLL1 | Immunoglobulin lambda-like polypeptide 1 | -5.32 | B cell |
| MYOM2 | Myomesin-2 | -4.96 | |
| CNTNAP2 | Contactin-associated protein-like 2 | -4.87 | B cell |
| FCGBP | Fc fragment of IgG binding protein | -4.43 | |
| TNFRSF17 | Tumor necrosis factor receptor superfamily member 17 | -4.22 | plasma cell |
| COBLL1 | Cordon-bleu protein-like 1 | -3.78 | B cell |
| VPREB3 | Pre-B lymphocyte protein 3 | -3.55 | B cell |
| TPM2 | Tropomyosin beta chain | -3.53 | |
| BACH2 | Transcription regular protein BACH2 | -3.52 | |
| EPHA1 | Ephrin receptor subfamily | -3.47 | T cell |
| SLC16A10 | Aromatic amino acid transporter | -3.16 | T cell |
| COCH | Coagulation factor C | -3.11 | |
| TAF15 | TAF15 RNA polymerase II | -3.04 | |
| OSBPL10 | Oxysterol binding protein-like 10 | -3.02 | B cell |
| EFHC2 | EF-hand domain (C-terminal) containing | -3.02 | |
| TCEA3 | Transcription elongation factor A | -2.81 | T cell |
| AXIN2 | Axin-like protein | -2.82 | T cell |
| KLHL3 | Kelch-like protein 3 | -2.81 | T cell |
*
fold change.