Table 2. Allele and genotype distributions of SNPs and association analysis of each SNP between Case and Control samples.
| SNPs | Sample | N | Genotype (%) | χ2 | P a | Allele (%) | χ2 | P a | OR (95% CI) | |||
| rs1387923 | T/T | T/C | C/C | T | C | |||||||
| Case | 402 | 237(59.0) | 138(34.3) | 27(6.7) | 2.98 | 0.23 | 612(76.1) | 192(23.9) | 2.36 | 0.12 | 1.19 (0.95∼1.49) | |
| Control | 406 | 2154(53.0) | 161(39.7) | 30 (7.4) | 591(72.8) | 221(27.2) | ||||||
| rs1565445 | T/T | T/C | C/C | T | C | |||||||
| Case | 402 | 186(46.3) | 169(42.0) | 47(11.7) | 1.30 | 0.52 | 541(67.3) | 263(32.7) | 1.25 | 0.26 | 0.89 (0.72∼1.09) | |
| Control | 406 | 172(42.2) | 181(44.6) | 53(13.1) | 525 (64.7) | 287(35.3) | ||||||
| rs2769605 | G/G | G/A | A/A | G | A | |||||||
| Case | 402 | 242(60.2) | 132(32.8) | 28(7.0) | 2.03 | 0.36 | 616 (76.6) | 188(23.4) | 2.03 | 0.52 | 0.93 (0.73∼1.17) | |
| Control | 406 | 246(60.6) | 141(34.7) | 19(4.7) | 633(78.0) | 179(22.0) | ||||||
| rs6265 | G/G | G/A | A/A | G | A | |||||||
| Case | 402 | 119(29.6) | 184(45.8) | 99(24.6) | 0.28 | 0.87 | 422(52.5) | 382(47.5) | 0.08 | 0.77 | 0.97 (0.80∼1.18) | |
| Control | 406 | 120(29.6) | 192(47.3) | 94(23.2) | 432(53.2) | 380(46.8) | ||||||
a
P-values are adjusted by Bonferroni method for the number of tests performed, the level of significance was set at 0.0125.