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. 2013 Sep 17;8(9):e74703. doi: 10.1371/journal.pone.0074703

Table 5. Association of the (C > T) rs2246833 polymorphism with coronary risk factors.

RAF Controls RAF Premature CAD MODEL OR (95% CI) P
Hypo-α-lipoproteinemia (n = 339) (n = 572) Recessive 2.51 (1.25-5.04) 0.0079
0.492 0.548
Additive 2.01 (1.31-3.10) 0.0011
Hypercholesterolemia (n = 245) (n = 198)
0.481 0.588 Additive 1.91 (1.10-3.34) 0.0200
Hypertriglyceridemia (n = 306) (n = 528) Recessive 2.02 (1.08-3.79) 0.0230
0.503 0.574
Additive 1.92 (1.30-2.83) 0.0008
Metabolic Syndrome (n = 277) (n = 428)
0.503 0.554 Additive 1.71 (1.19-2.45) 0.0033
Type 2 Diabetes Mellitus (n = 68) (n = 325) Recessive 2.08 (1.03-4.18) 0.0330
0.455 0.578
Additive 1.79 (1.17-2.74) 0.0062

All association were tested using logistic regression adjusted for age, gender, BMI, and medication when appropriate. (n) Represents the number of cases with each trait.

RAF: risk allele frequency.