TABLE V.
ROI Change Values for Normal Subjects (% Change Yearly) for KL and G-KL, Compared to Previously Published Results. Values in First Two Columns Are Derived From Jacobian Values Computed by KL and G-KL. For the Columns Showing Previous Studies, Percent Changes Given Over Period of N Years in the Study Are Converted to Annual Changes by the 1/N Root of the Changes Described in That Study. Boldface Results in the Columns of KL and G-KL Indicate Matches Within 20% of a Previously Published Value
| KL | G-KL | Walhovd 20111 | Walhovd 20052 | Raz 20103 | Raz 20054 | Gonoi 20095 | |
|---|---|---|---|---|---|---|---|
| Lat Vent | +1.28 | +1.86 | +1.92 | +2.20 | -- | -- | -- |
| CC | −0.03 | −0.13 | -- | -- | −0.46 | -- | |
|
Striatum
Gray |
0.00 | −0.04 | −0.38 | −0.25 | −0.42 | −0.79 | -- |
| Thalamus | −0.11 | −0.16 | −0.40 | −0.38 | -- | -- | -- |
|
Frontal
G+W |
−0.16 | −0.24 | -- | -- | -- | -- | −0.42 |
|
Templ
G+W |
−0.21 | −0.29 | -- | -- | -- | -- | −0.36 |
|
Cerebrum
Gray |
−0.24 | −0.35 | −0.45 | −0.42 | -- | -- | -- |
|
Cerebrum
White |
−0.15 | −0.21 | −0.35 | −0.27 | -- | -- | -- |
|
Cerebellum
Gray |
−0.29 | −0.37 | −0.31 | −0.38 | -- | -- | -- |
|
Cerebellum
White |
−0.25 | −0.40 | −0.34 | −0.36 | −0.72 | −0.66 | -- |
Notes on individual studies:
Values computed from [35] Table 3 giving mean volumes of structures by decade of age. Calculated annualized change from first decade to last, using N = 62 years.
Values computed from [34] Table 6 that gives adjusted ICV (intra-cranial volume) percent changes from age 20 to 90, N = 70 years.
Values computed from [33] Table 3 showing longitudinal change (N = 1.25 years) for mean volumes adjusted by ICV. Change is for δ12 only.
Values computed from [32] Table 1 that gave mean volumes at two intervals (N = 5 years).
Values computed from Gonoi et al. [36] using estimated volumes from their Fig. 2 regression plots by gender, right and left side, annualized using N = 55 years, then averaged for an overall value.