Regions of significantly lower gray matter volume in prenatally cocaine-exposed than noncocaine-exposed adolescents: (A) Crosshairs at x = −25, y = 1.5, z = −15; left insula and amygdala. (B–D) Crosshairs at x = 30, y = 1.5, z = −15; (B) right amygdala and inferior frontal gyrus; (C) ventral frontal cortical regions: orbitofrontal cortex and inferior frontal gyrus; (D) superior frontal gyrus, left and right amygdalae, and left insula. (E) Crosshairs at x = −19.5, y = −52.5, z = 63.0; posterior parietal cortex and superior frontal cortex shown. (F) Color bar representing the height of the voxelwise the t statistics in panels A–E.