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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cancer. 2013 Jun 21;119(18):3411–3418. doi: 10.1002/cncr.28203

Figure 1. NIR fluorescence imaging of colorectal liver metastases.

Figure 1

A colorectal liver metastasis (arrow) is clearly identified by a rim around the tumor in vivo (top row), 24 h after injection of 10-mg ICG. Normal liver tissue (arrowhead) shows minimal background uptake of ICG. In 5 patients, small, superficial, otherwise occult metastases (middle row, arrow) were identified by NIR fluorescence imaging. Benign lesions (bottom row, dashed arrow) could be differentiated from malignant lesions by a lack of a fluorescent rim around the lesion.