Table 3.
Mediation Models of Pre-Quit Effects of Naltrexone to Post-Quit Outcomes
| Outcomes | Naltrexone predicting outcome Post Quit Phasea | Naltrexone predicting effect in Pre Phase Quit | Prequit outcome as Mediator | Mediation ? | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B | se | p | B | se | p | B | se | p | ||
| At 4 Weeks after Quit Date | ||||||||||
| Δ Cigarettes Smoked | −2.60 | 1.24 | .04 | −1.28 | 0.51 | .01 | −2.31 | 1.25 | .07 | YES |
| Smoking Urge Ratings (B-QSU) | −3.27 | 1.49 | .02 | −0.25 | 0.07 | <.01 | −2.50 | 1.43 | .08 | YES |
| Δ Alcohol Drinks Consumed | −6.25 | 2.98 | .04 | −0.95 | 0.38 | .01 | −4.86 | 2.98 | .10 | YES |
| At 12 weeks after Quit Date | ||||||||||
| Δ Alcohol Drinks Consumed | −15.28 | 7.78 | .05 | −0.95 | 0.38 | .01 | −12.41 | 7.82 | .11 | YES |
Note. Data are the B, se, and p values in regression models for mediation analyses.
a
Post Quit phase refers to the period four weeks after the quit date for number of cigarettes smoked and smoking urge peak rating (B-QSU). For alcohol drinks consumed the post quit phase includes both four and twelve weeks after the quit date, as indicated.