Skip to main content
. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Addiction. 2013 Jul 5;108(10):1818–1828. doi: 10.1111/add.12250

Figure 1.

Figure 1

Observed CHRNA5-A3-B4 haplotype structure in Alaska-Native people.

The number in the squares indicate the r2 score.

Insert: A haplotype analysis revealed a 30kb region of high linkage disequilibrium between CHRNA5 and CHRNA3.Within this haplotype block, four haplotypes with a prevalence of more than 1% were identified. These four haplotype could be discerned by a few tag SNPs. For example, haplotype A was tagged by rs569207 in our sample (marker #5), while haplotype B was tagged by rs578776 in our sample (marker #8)