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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Addiction. 2013 Jul 5;108(10):1818–1828. doi: 10.1111/add.12250

Figure 4.

Figure 4

The combined impact of genetic variants in CHRNA5-A3-B4 and CYP2A6 activity on urinary TNE levels among the total tobacco user group. The low risk group included participants with both rs578776 AA genotype and slower CYP2A6 activity. Participants with either rs578776 AG/GG genotype or faster CYP2A6 activity were assigned to the intermediate risk group. Participants with both rs578776 AG/GG genotype and faster CYP2A6 activity were considered as the high risk group. IQR= interquartile range. The P-values were obtained by non-parametric comparisons (Mann-Whitney or Kruskal-Wallis).