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Best clinical response (as assessed by study investigators)
| Barasertib dose + LDAC 400 mg | |||
|---|---|---|---|
| Response, n (%) | 800 mg (n=6) |
1000 mg (n=13) |
1200 mg (n=3) |
| CR | 2 | 3 | 1 |
| CRi | 0 | 2 | 0 |
| PR | 1 | 1 | 0 |
| ORR | 3 (50) | 6 (46) | 1 (33) |
CR, complete response; CRi, complete response with incomplete recovery of neutrophils and/or platelets; PR, partial response; ORR, overall response rate
