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. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Brain Behav Immun. 2013 May 23;33:46–56. doi: 10.1016/j.bbi.2013.05.005

Representative (at 5× magnification) hematoxylin and eosin stained images (4a–4d, for SED/H₂O, FTR/H₂O, SED/DSS and FTR/DSS at disease peak Day 8, respectively). E, I and N, signify edema, inflammation, and necrosis, respectively. Quantification of images for percent necrotic tissue (4e) and inflammation (4f) scores (see methods for details). *denotes significant DSS-induced difference vs. SED/H₂O; + indicates a significant difference between FTR/H₂O and SED/H₂O groups. n = 10 and 13/group for Days 6 and 8, respectively and n = 9, 10, 10 and 7 for SED/H₂O, FTR/H₂O, SED/DSS and FTR/DSS, respectively for Day 12.

Representative (at 5× magnification) hematoxylin and eosin stained images (4a–4d, for SED/H₂O, FTR/H₂O, SED/DSS and FTR/DSS at disease peak Day 8, respectively). E, I and N, signify edema, inflammation, and necrosis, respectively. Quantification of images for percent necrotic tissue (4e) and inflammation (4f) scores (see methods for details). *denotes significant DSS-induced difference vs. SED/H₂O; + indicates a significant difference between FTR/H₂O and SED/H₂O groups. n = 10 and 13/group for Days 6 and 8, respectively and n = 9, 10, 10 and 7 for SED/H₂O, FTR/H₂O, SED/DSS and FTR/DSS, respectively for Day 12.