TABLE 1.
Characteristics of first primary colorectal cancer (CRC) cases according to occurrence and site of second primary cancer, SEER 13 [1992–2009]
| All 1st Primary CRC Cases N (col %) | Cases who Developed a 2nd Primary Cancer |
||
|---|---|---|---|
| All 2nd Primary Sites N (col %) | 2nd Primary CRC N (col %) | ||
| Age at 1st CRC diagnosis | |||
| 40–49 | 16,834 (10) | 675 (5) | 206 (7) |
| 50–59 | 38,679 (23) | 2,359 (16) | 499 (17) |
| 60–69 | 53,089 (31) | 5,163 (35) | 904 (32) |
| 70–79 | 61,557 (36) | 6,683 (45) | 1,245 (44) |
| Sex | |||
| Male | 92,299 (54) | 9,029 (61) | 1,594 (56) |
| Female | 77,860 (46) | 5,851 (39) | 1,260 (44) |
| Race | |||
| White non-Hispanic | 117,125 (69) | 10,923 (73) | 1,984 (70) |
| Black | 18,493 (11) | 1,618 (11) | 369 (13) |
| White Hispanic | 14,600 (9) | 998 (7) | 246 (9) |
| American Indian/Alaska Native | 778 (0.5) | 67 (0.5) | 10 (0.4) |
| Asian or Pacific Islander | 18,032 (11) | 1,263 (8) | 240 (8) |
| Other/unspecified | 1,131 (1) | 11 (0.1) | 5 (0.2) |
| Stage at 1st CRC diagnosis | |||
| Localized | 71,436 (42) | 8,000 (54) | 1,349 (47) |
| Regional | 64,925 (38) | 5,764 (39) | 1,183 (41) |
| Distant | 29,837 (18) | 801 (5) | 216 (8) |
| Unstaged | 3961 (2) | 315 (2) | 106 (4) |
| Site of 1st CRC | |||
| Cecum | 25,856 (15) | 2,231 (15) | 380 (13) |
| Ascending colon | 18,615 (11) | 1,743 (12) | 267 (9) |
| Hepatic flexure | 5,923 (3) | 549 (4) | 103 (4) |
| Transverse colon | 9,757 (6) | 945 (6) | 218 (8) |
| Splenic flexure | 4,365 (3) | 432 (3) | 130 (5) |
| Descending colon | 7,624 (4) | 784 (5) | 185 (6) |
| Sigmoid colon | 41,829 (25) | 3,880 (23) | 761 (27) |
| Rectosigmoid junction | 16,952 (10) | 1,418 (10) | 275 (10) |
| Rectum | 39,238 (23) | 2,898 (19) | 535 (19) |
| SEER Registry * | |||
| San Francisco-Oakland | 18,826 (11) | 1,553 (10) | 283 (10) |
| Connecticut | 19,001 (11) | 1,812 (12) | 300 (11) |
| Detroit | 20,429 (12) | 2,106 (14) | 425 (15) |
| Hawaii | 7,033 (4) | 536 (4) | 95 (3) |
| Iowa | 17,390 (10) | 1,672 (11) | 314 (11) |
| New Mexico | 7,491 (4) | 539 (4) | 96 (3) |
| Seattle-Puget Sound | 17,277 (10) | 1,579 (11) | 245 (9) |
| Utah | 6,472 (4) | 500 (3) | 100 (4) |
| Atlanta | 10,250 (6) | 731 (5) | 138 (5) |
| San Jose-Monterey | 9,119 (5) | 706 (5) | 117 (4) |
| Los Angeles | 36,203 (21) | 3,093 (21) | 731 (26) |
| Rural Georgia | 668 (0.4) | 53 (0.4) | 10 (0.4) |
*
Excludes Alaska Native Tumor Registry, which is not included in SEER multiple primary data files.