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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Am J Transplant. 2013 Aug 5;13(9):2293–2307. doi: 10.1111/ajt.12372

Figure 10. Intragraft cytokine and chemokine mRNA expression in cardiac isografts and in allografts from anti-LFA-1 mAb treated recipients.

Figure 10

Groups of C57BL/6 mice were treated with 200 μg control rat IgG or with anti-CD4 or anti-CD154 mAb either on days −1 and 0. The mice received isografts or complete MHC mismatched A/J cardiac allografts on day 0. Grafts were harvested on day 7 post-transplant, whole cell RNA was isolated from graft homogenates, and quantitative real-time PCR was used to measure expression levels of mRNA encoding the indicated cytokines, chemokines and phenotypic markers. *p ≤ 0.05; **p < 0.01; n.s. not significantly different.