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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Am J Transplant. 2013 Aug 5;13(9):2293–2307. doi: 10.1111/ajt.12372

Figure 4. Neutrophil activation in cardiac allografts from recipients treated with anti-LFA-1 mAb.

Figure 4

Groups of C57BL/6 mice were treated with 200 μg anti-LFA-1 mAb either on days −1 and 0 or on days 3 and 4 or with control rat IgG on days 3 and 4. The mice received isografts or complete MHC mismatched A/J cardiac allografts on day 0. Grafts were harvested on day 7 post-transplant, soluble lysates were prepared and the total protein in the lysates determined. Aliquots of the lysate were tested by ELISA for quantity of myeloperoxidase (MPO) protein as a measure of neutrophil activation in the graft. *p ≤ 0.02.