Fig. 1.

Kaplan–Meier plot with data expressed as percentage of individuals alive (a, b) and median life span of the four groups studied (c). Mantel–Cox log-rank test analysis reveals a shift to the right for the resveratrol group in SAMP8 (a, P < 0.0001) and SAMR1 (b, P = 0.0051). In the median life span comparison (c) and maximum life span comparison considered as the mean of the final 20 % of mice surviving in each group (d), results are expressed as mean±SEM; ***P < 0.001 vs. SAMP8, ^##P < 0.01 vs. SAMR1, ^###P < 0.001 vs. SAMR1